Permethrin Cream

What is Permethrin Cream?

Permethrin cream is a topical medication used to treat infestations of small insects on the skin and hair, including lice and scabies mites, which cause irritation and itching. It contains permethrin, a synthetic insecticide, and is safe for human skin when used properly. The cream is available in different strengths:

• 5% cream for scabies

• 1% lotion or rinse for head lice

Permethrin targets the insects directly and remains largely on the skin’s surface, causing minimal absorption into the body.

Overview & Description

• Drug Class: Pyrethroid insecticide

• Mechanism: Works by affecting the nervous system of insects, causing paralysis and death

• Application: Topical, applied directly to the skin or hair

Permethrin is chemically derived from natural compounds found in chrysanthemums but has been enhanced for longer-lasting efficacy while remaining safe for humans.

Uses of Permethrin Cream

• Scabies: Eliminates mites and eggs, reducing itching and irritation caused by burrowing mites.

• Head Lice: Treats lice and nits on the scalp.

• Pubic Lice: Sometimes prescribed, though other medications may also be recommended.

• Other Mite Infestations: Safe alternative for patients who cannot take oral treatments.

How Does Permethrin Work?

Permethrin affects insect nervous systems by keeping sodium channels open, causing paralysis and death of the mites or lice. Human nerve cells recover quickly, making it safe for topical use.

Benefits of Permethrin Cream

• High success rate in one treatment

• Eliminates both mites/lice and eggs

• Safe for infants (2 months and older) and older adults

• Less odor and staining compared to older treatments

• Minimal interference with other medications

Side Effects

Common:

• Redness, itching, stinging, or burning at the application site

Rare:

• Swelling, rash, allergic reactions

• Persistent scabies itching due to body response to dead mites

Seek immediate medical care if severe allergic reactions occur (e.g., difficulty breathing, facial swelling, profuse rash).

Directions for Use

For Scabies (5% cream):

1. Apply to clean, dry skin from neck down, including elbows, under nails, armpits, groin, buttocks, and soles.

2. Leave on for 8–14 hours, then rinse thoroughly.

3. Repeat after 1 week if needed.

For Head Lice (1% lotion/rinse):

1. Apply to washed, towel-dried hair, especially behind ears and neck.

2. Leave for 10 minutes, then rinse.

3. Remove dead lice/nits with a fine-tooth comb.

4. Repeat treatment after 7 days if necessary.

Precautions & Warnings

• Do not use on open wounds, broken skin, or infants under 2 months without a doctor’s advice.

• Avoid contact with eyes and mouth.

• Notify your doctor if you have asthma, other respiratory issues, or severe allergies.

• Even after successful treatment, itching may last for weeks due to body reactions.

• Do not share clothing, towels, or bedding until infestation is cleared.

Drug Interactions

• Minimal absorption means few drug interactions.

• Consult your physician if using other topical medications on the same area.

General Instructions & Lifestyle Advice

• Apply only to clean, dry skin or hair.

• Wash hands after application.

• Wash all recently used clothing, bedding, and towels in hot water.

• Treat all household members if infested.

• Avoid close contact until treatment is complete.

No special diet is required; normal eating habits are fine.

Comparison with Other Treatments

• Lindane: More neurotoxic; less safe than permethrin.

• Malathion Lotion: Effective but flammable and pungent.

• Crotamiton: Requires multiple applications and may be less effective.

Permethrin offers a combination of safety, effectiveness, and convenience, making it the preferred first-line treatment for lice and scabies.

Buy Permethrin Cream

Onco India International is a trusted manufacturer, supplier, wholesaler, and exporter of Permethrin Cream. For authentic products or bulk orders, contact Onco India International directly.