Promethazine Cream 2% – Overview

Promethazine Cream 2% is an FDA-approved topical formulation widely used to manage various skin conditions. It contains 2% Promethazine, a powerful antihistamine, that provides long-lasting relief from itching, redness, swelling, and irritation caused by allergic skin reactions and other dermatological issues.

Unlike oral antihistamines, Promethazine Cream targets only the affected area, offering localized relief with minimal systemic side effects. The cream is also enriched with soothing agents and emollients, which help nourish and smoothen the skin while restoring its natural barrier function.

What is Promethazine Cream?

Promethazine Cream is a topical antihistamine-based medication that effectively reduces inflammation, itching, and discomfort associated with:

• Skin allergies

• Rashes

• Hives

• Insect bites

• Minor burns

• Contact dermatitis

By blocking histamine receptors in the skin, the cream helps to quickly reduce itching and irritation, making it a fast-acting and reliable solution for acute skin flare-ups.

Manufacturer – Onco India International

Onco India International is a trusted global pharmaceutical provider recognized for delivering high-quality, safe, and effective dermatological solutions. With a strong commitment to healthcare standards, Onco India International ensures that Promethazine Cream 2% meets the highest levels of purity, efficacy, and patient safety.

Key Ingredient & Its Benefits

• Promethazine (2%) – An effective antihistamine that:

  • Blocks histamine activity in the skin

  • Relieves itching, redness, and swelling

  • Reduces allergic responses and irritation

Additional soothing emollients in the cream help to:

• Moisturize the skin

• Support barrier repair

• Enhance comfort and smoothness

Benefits & Indications

• Quick relief from itching, rashes, and redness

• Effective against insect bites, hives, and minor burns

• Reduces skin inflammation and swelling

• Helps prevent scratching that can worsen irritation

• Compact and portable – convenient for use anytime, anywhere

How Promethazine Cream Works

Promethazine acts by blocking histamine receptors in the skin, thereby:

• Minimizing allergic responses

• Reducing swelling and redness

• Providing rapid comfort in acute skin conditions

With regular use, it helps to:

• Maintain smoother skin

• Reduce flare-ups of itching

• Improve overall skin comfort

How to Apply

1. Clean and dry the affected area before use.

2. Apply a thin, even layer of the cream.

3. Use only the prescribed amount.

4. Wash hands thoroughly after application.

Possible Side Effects

• Mild redness or irritation

• Itching or stinging sensation

• Allergic skin reaction (rare)

Precautions & Safety Measures

• Avoid contact with eyes, mouth, or nose.

• Do not apply on open wounds, broken, or infected skin.

• Use in children only under medical supervision.

• Avoid prolonged or excessive use without a doctor’s advice.

• Treated skin may be more sensitive to sunlight – limit sun exposure.

• Discontinue use if severe allergic reaction occurs.

Contraindications

• Individuals allergic to Promethazine or related compounds

• Should be used with caution during pregnancy and breastfeeding (consult doctor)

Special Instructions

• Do not cover treated skin with a bandage unless advised by a healthcare professional.

• Avoid alcohol, smoking, or other irritants that may worsen skin reactions.

• Store in a cool, dry place away from direct sunlight.

Conclusion

Promethazine Cream 2% from Onco India International is a safe, effective, and trusted solution for allergic skin reactions, itching, and irritation. By combining the benefits of antihistamine action with skin-soothing properties, it offers quick relief, improved comfort, and healthier skin when used as directed.