Diltiazem HCI Tablets

Product/Composition Diltiazem HCI Tablets
Strength 30mg, 60mg, 90mg, 120mg
Form Tablets
Production Capacity 10 Million Tablet/Month
Packaging 10 X 10 Tablets / Box
Therapeutic use Cardiovascular
Package Insert/Leaflet Available upon request

Diltiazem HCl Tablets are a medicine classified as a calcium channel blocker. They are mainly used to manage cardiovascular conditions by relaxing blood vessels and reducing the workload on the heart.

Here are the key details:

  • Composition: Each tablet contains Diltiazem hydrochloride as the active ingredient, available in various strengths such as 30 mg, 60 mg, 90 mg, and 120 mg.

  • Dosage Form: Oral tablets, sometimes immediate-release or sustained-release (SR/extended-release).

  • Mode of Action: Diltiazem works by blocking calcium channels in the heart and blood vessel walls, which:

    • Relaxes blood vessels, lowering blood pressure.

    • Reduces heart rate and the heart’s oxygen demand.

    • Helps improve blood flow to the heart muscle.

  • Uses:

    • Hypertension (high blood pressure)

    • Angina pectoris (chest pain due to reduced blood flow to the heart)

    • Certain arrhythmias (irregular heartbeats), such as atrial fibrillation or atrial flutter

  • Treatment Goal: To lower blood pressure, prevent chest pain, and control heart rhythm disturbances.

  • Side Effects:

    • Common: headache, dizziness, flushing, nausea, constipation, fatigue.

    • Less common/serious: slow heart rate (bradycardia), low blood pressure (hypotension), swelling of legs or feet, worsening heart failure in some patients.

  • Precautions:

    • Should be used cautiously in patients with low blood pressure, severe heart failure, or sick sinus syndrome.

    • Monitoring of heart rate and blood pressure is recommended.

    • Interactions can occur with other blood pressure medications, certain anti-arrhythmic drugs, and some antifungals or antibiotics.

    • Not typically recommended during pregnancy unless specifically advised by a doctor.

👉 Diltiazem can be used either as a short-term relief for angina or as a long-term therapy for blood pressure and heart rhythm control.