Ethinylestradiol and Cyproterone Acetate Tablets are a combination medicine that contains an estrogen (Ethinylestradiol) and a progestin with anti-androgenic properties (Cyproterone Acetate). They are primarily used for hormonal regulation and management of androgen-related conditions in women.

Here are the key details:

• Composition: Each tablet contains:

  • Ethinylestradiol – a synthetic estrogen.

  • Cyproterone Acetate – a synthetic progestin with anti-androgen activity.

  • Available in fixed doses such as 2 mg Cyproterone + 0.035 mg Ethinylestradiol.

• Dosage Form: Oral tablets, usually taken once daily in a 21-day cycle followed by a 7-day break (or as prescribed by a doctor).

• Mode of Action:

  • Ethinylestradiol: Provides estrogen support, regulates menstrual cycles, and enhances contraceptive effectiveness.

  • Cyproterone Acetate: Blocks androgen receptors, reducing the effects of male hormones (androgens) such as excessive hair growth and acne.

  • Together, they also inhibit ovulation, providing contraceptive effect.

• Uses:

  • Severe acne or seborrhea due to excess androgens.

  • Hirsutism (excessive facial or body hair) in women.

  • Polycystic ovary syndrome (PCOS) – for hormonal regulation and symptom management.

  • Contraception – prevents pregnancy through suppression of ovulation.

• Treatment Goal: To reduce androgen-related symptoms, regulate menstrual cycles, and provide reliable contraception.

• Side Effects:

  • Common: nausea, headache, breast tenderness, mood changes, weight gain, menstrual irregularities.

  • Less common/serious: blood clots, high blood pressure, liver issues, depression, or allergic reactions.

• Precautions:

  • Not recommended in women with a history of blood clots, stroke, liver disease, or estrogen-sensitive cancers.

  • Avoid smoking, especially over age 35, due to increased cardiovascular risk.

  • Regular monitoring may be required for blood pressure and liver function during prolonged use.

  • Effectiveness is reduced if tablets are missed or not taken as prescribed.

👉 This combination is particularly useful when women need both hormonal regulation and anti-androgen benefits, such as for severe acne, hirsutism, or PCOS, while also providing contraceptive protection.