Gemcitabine Hydrochloride Citafine
| Product/Composition | Gemcitabine Hydrochloride |
|---|---|
| Strength | 200mg, 1000mg |
| Form | Injection |
| Production Capacity | 10 Million Vials/Month |
| Packaging | 1 Vial / Box |
| Therapeutic use | Cancer Treatment / Chemotherapy |
| Package Insert/Leaflet | Available upon request |
| Brand Name | Citafine |
Citafine contains Gemcitabine Hydrochloride, an antimetabolite chemotherapy medicine used as part of treatment regimens for several types of cancer. Gemcitabine is a pyrimidine nucleoside analogue that interferes with DNA synthesis, thereby limiting the growth and survival of rapidly dividing cancer cells.
Gemcitabine Hydrochloride is administered by intravenous infusion under the supervision of an oncologist or qualified healthcare professional. The dosage and treatment schedule depend on the cancer type, chemotherapy regimen, blood counts, organ function, and the patient’s overall condition.
What is Gemcitabine Hydrochloride?
Gemcitabine Hydrochloride is an antimetabolite and pyrimidine nucleoside analogue. After entering cells, it is converted into active metabolites that interfere with nucleotide metabolism and DNA synthesis.
It may be used alone or in combination with other anticancer medicines according to established oncology treatment protocols.
Benefits / Uses
Citafine (Gemcitabine Hydrochloride) may be used as part of chemotherapy regimens for:
- Pancreatic cancer
- Non-small cell lung cancer
- Breast cancer
- Ovarian cancer
- Bladder cancer
- Other selected malignancies according to specific treatment protocols
The exact indication and combination regimen should be determined by the treating oncologist.
Dosage Guidelines
Gemcitabine Hydrochloride is administered intravenously, with the dosage and schedule individualized according to the prescribed chemotherapy protocol.
Important considerations include:
- Treatment frequency and dosage depend on the cancer type and combination regimen.
- Complete blood counts should be monitored before and during treatment.
- Kidney and liver function may need to be assessed.
- Treatment may be delayed or adjusted if blood counts or organ function are significantly affected.
- Patients should be monitored for chemotherapy-related adverse effects.
Gemcitabine should only be administered under specialist medical supervision.
Wholesale & Supply
Citafine (Gemcitabine Hydrochloride) can be considered for pharmaceutical wholesale and institutional supply, subject to applicable regulatory requirements, market authorization, and destination-country regulations.
For bulk procurement, buyers can request information regarding:
- Available strengths and presentations
- Packaging configuration
- Batch details
- Certificate of Analysis (CoA)
- Manufacturing documentation
- Export and shipping documentation
Buying Online
Gemcitabine Hydrochloride is a prescription chemotherapy medicine and should be sourced only through authorized pharmaceutical distributors, hospitals, pharmacies, or other licensed healthcare channels.
Reviews
Individual responses to Gemcitabine can vary depending on cancer type, treatment regimen, dosage, and patient-specific factors. Treatment outcomes and tolerability should be evaluated by the treating oncology team.
Quality Assurance
Gemcitabine Hydrochloride injectable products should undergo appropriate pharmaceutical quality-control testing for parameters such as identity, strength, purity, sterility, and other applicable specifications for injectable medicines.
Frequently Asked Questions
What is Citafine used for?
Citafine contains Gemcitabine Hydrochloride and may be used as part of chemotherapy regimens for pancreatic, lung, breast, ovarian, bladder, and other selected cancers.
What type of medicine is Gemcitabine Hydrochloride?
Gemcitabine Hydrochloride is an antimetabolite chemotherapy medicine and pyrimidine nucleoside analogue.
How is Citafine administered?
Citafine is administered by intravenous infusion by qualified healthcare professionals according to the prescribed chemotherapy protocol.
What are the important side effects of Gemcitabine?
Important adverse effects may include reduced blood-cell counts, fatigue, nausea and vomiting, rash, fever, and changes in liver function. Appropriate monitoring is required during treatment.
Can Gemcitabine be combined with other chemotherapy medicines?
Yes. Gemcitabine is frequently used in combination with other anticancer medicines depending on the cancer diagnosis and treatment protocol.
Does Gemcitabine require blood-test monitoring?
Yes. Blood counts are generally monitored because Gemcitabine can cause myelosuppression. Kidney and liver function may also be assessed when clinically appropriate.
Who should administer Gemcitabine?
Gemcitabine should be administered by qualified healthcare professionals experienced in the use of cytotoxic chemotherapy, with appropriate monitoring facilities available.
Conclusion
Citafine (Gemcitabine Hydrochloride) is an established antimetabolite chemotherapy medicine used in multiple oncology treatment protocols. By interfering with DNA synthesis, Gemcitabine helps inhibit the proliferation of cancer cells. Because treatment can cause myelosuppression and other adverse effects, its use requires specialist supervision and appropriate laboratory monitoring.


