Vinblastine Sulphate Injection Uniblastin

Product/Composition Vinblastine Sulphate Injection
Strength 10mg
Form Injection
Production Capacity 10 Million Vials/Month
Packaging 1 Vial / Box
Therapeutic use Hodgkin Lymphoma, Non-Hodgkin Lymphoma & Selected Solid Tumors
Package Insert/Leaflet Available upon request
Brand Name Uniblastin

Vinblastine Sulphate Injection – Uniblastin contains Vinblastine Sulphate, a vinca alkaloid antineoplastic medicine used as part of combination chemotherapy for various cancers and hematological malignancies.

Vinblastine works by binding to tubulin and interfering with microtubule formation, which prevents cell division and inhibits the proliferation of rapidly dividing cancer cells. It is administered parenterally under the supervision of qualified healthcare professionals.

Vinblastine is commonly incorporated into combination chemotherapy protocols for conditions such as Hodgkin lymphoma, non-Hodgkin lymphoma, testicular cancer, breast cancer, and other selected malignancies, depending on the treatment protocol.

What is Vinblastine Sulphate?

Vinblastine Sulphate is a vinca alkaloid and cytotoxic antineoplastic agent. It inhibits microtubule formation by interfering with tubulin, thereby disrupting mitosis and cancer-cell division.

It is generally used as part of a combination chemotherapy regimen rather than as a standalone treatment.

Benefits / Uses

Uniblastin may be used in appropriate chemotherapy protocols for:

  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
  • Testicular cancer
  • Breast cancer
  • Kaposi sarcoma
  • Other selected hematological and solid malignancies

The exact indication and combination regimen depend on the patient’s diagnosis and the oncologist’s treatment protocol.

Dosage Guidelines

Vinblastine Sulphate Injection must be administered only by qualified healthcare professionals according to the prescribed chemotherapy regimen.

  • The dose is individualized according to the indication, body surface area, blood counts, and treatment protocol.
  • Administration is generally by the intravenous route.
  • Blood counts should be monitored regularly because bone-marrow suppression is a major dose-limiting toxicity.
  • Dose adjustments or treatment delays may be required based on blood-count results and other toxicities.
  • Liver function and other relevant clinical parameters may also require monitoring.
  • Vinblastine must never be administered intrathecally, as this can be fatal.

The exact dose, frequency, dilution, and administration procedure should follow the approved product information and specialist oncology protocol.

Wholesale & Supply

Uniblastin – Vinblastine Sulphate Injection can be supplied to hospitals, oncology centers, pharmaceutical distributors, wholesalers, and international healthcare markets, subject to applicable regulatory requirements.

Bulk buyers can request:

  • Available strengths and presentations
  • Packaging configuration
  • Minimum order quantity
  • Production and supply capacity
  • Certificate of Analysis (CoA)
  • Product documentation
  • Regulatory and export documents

Buying Online

Vinblastine Sulphate is a prescription cytotoxic chemotherapy medicine and should only be procured through authorized pharmaceutical suppliers and administered in an appropriate healthcare setting.

Hospitals, licensed distributors, and healthcare procurement organizations can contact the supplier for product availability, quotations, and applicable documentation.

Reviews

Individual responses to Vinblastine-based chemotherapy vary according to cancer type, disease stage, treatment regimen, previous therapies, and patient-specific factors. Clinical decisions should therefore be based on the treating oncologist’s assessment rather than individual product reviews.

Quality Assurance

Uniblastin should be manufactured and handled according to applicable pharmaceutical quality standards. Quality-control testing for injectable products may include:

  • Identification and assay
  • Purity and related substances
  • Sterility
  • Bacterial endotoxins
  • Particulate matter
  • pH and appearance
  • Stability testing
  • Container-closure integrity

Product-specific quality and regulatory documentation can be provided upon request, where applicable.

Frequently Asked Questions

What is Uniblastin used for?

Uniblastin contains Vinblastine Sulphate and may be used in combination chemotherapy protocols for Hodgkin lymphoma, non-Hodgkin lymphoma, testicular cancer, breast cancer, Kaposi sarcoma, and other selected malignancies.

What type of medicine is Vinblastine Sulphate?

Vinblastine Sulphate is a vinca alkaloid and cytotoxic antineoplastic medicine that interferes with microtubule formation and cell division.

How is Vinblastine Injection administered?

Vinblastine is administered intravenously by qualified healthcare professionals according to the prescribed chemotherapy protocol.

Can Vinblastine be administered intrathecally?

No. Vinblastine must not be administered intrathecally because this can result in fatal toxicity.

What are the important side effects of Vinblastine?

Important adverse effects may include bone-marrow suppression, leukopenia, anemia, thrombocytopenia, gastrointestinal symptoms, constipation, hair loss, and injection-site complications. The risk and severity depend on the treatment regimen.

Does Vinblastine require blood-count monitoring?

Yes. Regular blood-count monitoring is important because myelosuppression is a major toxicity of Vinblastine and may require dose modification or treatment interruption.

Conclusion

Uniblastin – Vinblastine Sulphate Injection is a vinca alkaloid chemotherapy medicine that inhibits microtubule formation and cancer-cell division. It is used in selected hematological malignancies and solid tumors, generally as part of combination chemotherapy. Because of its cytotoxic effects and risk of serious toxicity, administration and monitoring should be performed under specialist oncology supervision.