Albendazole Tablets – Broad-Spectrum Antiparasitic

Albendazole is a widely used broad-spectrum anthelmintic medication effective against numerous types of parasitic worm infections. Belonging to the benzimidazole class, Albendazole works by blocking tubulin polymerization in parasites, reducing the number of microtubules in their intestinal cells. This disrupts their metabolism, leading to energy depletion, cellular damage, and eventual death of the parasite.

Albendazole is prescribed extensively in both human healthcare and veterinary medicine, as well as in global deworming initiatives.

Therapeutic Uses

Albendazole is effective in treating a wide range of parasitic infections, including:

• Neurocysticercosis – caused by Taenia solium (pork tapeworm)

• Hydatid Disease – caused by Echinococcus granulosus

• Hookworm Infections – Ancylostoma duodenale, Necator americanus

• Ascariasis – caused by Ascaris lumbricoides

• Trichuriasis – caused by Trichuris trichiura

• Enterobiasis – caused by Enterobius vermicularis

• Strongyloidiasis – caused by Strongyloides stercoralis

• Giardiasis – particularly in children, caused by Giardia lamblia

• Filariasis – as part of mass drug administration programs for lymphatic filariasis elimination

Mechanism of Action

Albendazole works by inhibiting microtubule synthesis in parasitic worms. This halts nutrient uptake, depletes their energy reserves, and damages cell structures—leading to the parasite’s death.

In conditions such as neurocysticercosis, Albendazole helps reduce inflammation and damage caused by dying larvae in the brain.

Key Advantages

• Effective against a broad range of parasitic infections

• Widely used in international deworming campaigns

• Suitable for single-dose or extended treatment courses

• Available in multiple forms: chewable tablets and oral suspensions

• Affordable and generally well-tolerated with minimal side effects

Before Taking Albendazole

• Inform your doctor of any liver disease, history of bone marrow suppression, or drug allergies

• Long-term use requires regular liver function tests

• Take with food, preferably fatty meals, for better absorption

• Avoid grapefruit juice as it may interfere with drug metabolism

Dosage Guidelines

Dosage depends on the infection type and patient profile:

• Neurocysticercosis: 400 mg twice daily for 8–30 days

• Hydatid Disease: 400 mg twice daily for 28 days (repeat cycles may be necessary)

• Intestinal Worm Infections: Single 400 mg dose

• Strongyloidiasis / Taeniasis: 400 mg daily for 3 days

• Giardiasis (Children): 400 mg daily for 5 days

Missed Dose

If missed, take as soon as remembered. If it is close to your next scheduled dose, skip the missed dose—do not double up.

Possible Side Effects

• Headache

• Dizziness

• Nausea, vomiting, abdominal pain

• Elevated liver enzymes

• Temporary hair loss (reversible)

• Rare: bone marrow suppression, liver toxicity, severe allergic reactions

Drug Interactions

Albendazole may interact with:

• Cimetidine – increases blood levels of Albendazole

• Dexamethasone – enhances metabolism

• Praziquantel – boosts bioavailability

• Rifampicin, Phenobarbital, Phenytoin – reduce concentration

• Ketoconazole, Erythromycin – increase concentration

• Warfarin – increases bleeding risk

Special Precautions

• Avoid alcohol during treatment to reduce risk of liver damage

• Not recommended during the first trimester of pregnancy

• Women of childbearing age should use effective contraception during treatment and for 1 month after

• Monitor blood counts in patients with bone marrow disorders

Storage

• Store at 15–30°C, in a dry place away from light

• Keep out of reach of children

Onco India International – Trusted Albendazole Supplier

Onco India International is a reputed manufacturer and global exporter of high-quality Albendazole formulations for both human and veterinary applications.

We ensure:

• GMP-certified manufacturing

• Stringent quality control for safety and efficacy

• Competitive pricing for bulk orders

• Worldwide delivery with complete regulatory documentation

For premium-grade Albendazole Tablets and suspensions, trust Onco India International—your reliable partner in antiparasitic medication supply.