Amantadine Hydrochloride (HCl) Tablets

Manufactured by Onco India International

Overview

Amantadine Hydrochloride (HCl) is a prescription medication used for a variety of neurological and viral conditions. It is widely prescribed for:

• Parkinson’s disease and related movement disorders (Parkinsonism)

• Influenza A virus infections (prevention and treatment)

• Drug-induced extrapyramidal symptoms caused by certain medications

Amantadine acts both as an antiviral agent and a dopamine agonist, making it effective for improving motor function in Parkinson’s disease and reducing viral replication in influenza infections.

Uses

Amantadine HCl tablets are primarily prescribed for:

1. Parkinson’s Disease & Parkinsonism – Helps reduce tremors, muscle stiffness, and slowness of movement (bradykinesia). May be used alone or with other drugs like Levodopa for better results.

2. Influenza A Virus – Prevents and treats influenza A by stopping the virus from multiplying.

3. Drug-Induced Movement Disorders – Relieves tremors and rigidity caused by certain antipsychotic medications.

Benefits

• Improves motor function and flexibility in Parkinson’s disease

• Reduces the severity and duration of influenza A symptoms

• Helps manage side effects of other medications affecting movement

How It Works

Amantadine works in two ways:

• Neurological effect: Stimulates dopamine receptors in the brain, enhancing dopamine activity and improving muscle control.

• Antiviral effect: Blocks the uncoating of the influenza A virus, preventing it from multiplying and spreading.

Dosage & Administration

• Form: Oral tablets

• Usual dose for Parkinson’s disease: 100 mg daily, adjusted as needed by a doctor.

• Usual dose for influenza prevention: 200 mg per day for adults.

• Directions: Swallow whole with a full glass of water. Preferably take with food to minimize stomach upset.

When Not to Use

Avoid Amantadine if you:

• Are allergic to it or any ingredient in the tablet

• Have severe kidney or liver disease

• Have a history of seizures

Drug Interactions

• With caution: Anticholinergics, diuretics, and other CNS medications (antidepressants, antipsychotics, dopaminergic drugs)

• Always inform your doctor about all medications and supplements you take

Precautions

• Kidney & Liver Function: Dose adjustments may be required

• Elderly patients: Higher risk of confusion, hallucinations, or dizziness

• Pregnancy & breastfeeding: Use only if benefits outweigh potential risks

• Do not stop suddenly—taper gradually under medical supervision

Possible Side Effects

• Dizziness or lightheadedness

• Dry mouth

• Nausea

• Swelling in ankles or feet

• Confusion or hallucinations (more common in elderly)

Seek immediate medical help if you experience severe allergic reactions or irregular heartbeat.

Lifestyle & Supportive Care

• Parkinson’s: Engage in regular physical therapy and maintain a balanced diet rich in antioxidants, fiber, and healthy fats.

• Influenza: Rest, stay hydrated, and follow your doctor’s antiviral treatment plan.

Storage

• Store at room temperature, away from moisture and light

• Keep out of reach of children

• Do not use after the expiry date printed on the packaging