Bexarotene Capsules

Product/Composition Bexarotene Capsules
Form Capsule
Strength 75mg
Therapeutic use Anti Cancer
Package Insert/Leaflet Available upon request

What is Bexarotene 75 mg Capsule?

Bexarotene 75 mg Capsule is an anticancer medication used primarily in the treatment of cutaneous T-cell lymphoma (CTCL), a rare type of cancer that affects the skin. It belongs to a class of drugs known as retinoids (rexinoids), which regulate the growth and differentiation of cancer cells.

This medicine is typically prescribed for patients whose disease has not responded to other systemic therapies, helping to control symptoms and slow disease progression.


Description

Bexarotene 75 mg Capsule is an oral chemotherapy drug designed to target abnormal T-cells involved in CTCL. It works by activating specific receptors that influence gene expression, ultimately controlling the growth and spread of cancerous cells.

The capsule formulation allows convenient dosing and is often used as part of long-term therapy under specialist supervision.

Uses of Bexarotene 75 mg Capsule

  • Treatment of cutaneous T-cell lymphoma (CTCL)
  • Management of skin-related lymphoma symptoms
  • Used in patients resistant to other systemic treatments
  • Helps control progression of T-cell malignancies

Indications

  • Indicated for adult patients with CTCL
  • Used in advanced or refractory cases
  • Prescribed under the supervision of an oncologist or dermatologist
  • Dose may vary depending on body surface area and response

Benefits

  • Targets abnormal T-cells specifically
  • Helps reduce skin lesions and associated symptoms
  • Slows disease progression
  • Oral capsule provides convenient administration
  • Improves quality of life in patients with CTCL

Drug Interactions

Bexarotene may interact with the following medications:

  • Ketoconazole, Itraconazole
  • Gemfibrozil
  • Rifampin
  • Insulin or oral antidiabetic drugs
  • Thyroid hormone medications

Avoid vitamin A supplements unless advised by your doctor. Always inform your doctor about all medications and supplements before starting treatment.

How Bexarotene Works

  • Activates retinoid X receptors (RXRs)
  • Regulates gene expression in cancer cells
  • Controls abnormal cell growth and differentiation
  • Promotes apoptosis (death) of malignant T-cells

Warnings & Precautions

  • May increase blood lipid levels—regular monitoring required
  • Can affect thyroid function
  • Risk of liver toxicity—monitor liver function tests
  • Strictly contraindicated during pregnancy (teratogenic risk)
  • Use effective contraception during treatment

General Instructions

  • Take the capsule once daily with food as prescribed
  • Swallow whole with water; do not crush or chew
  • Follow your doctor’s dosing schedule strictly
  • Do not stop medication without medical advice
  • Regular monitoring tests are essential

Storage Information

  • Store in a cool, dry place away from direct sunlight
  • Keep in original packaging
  • Keep out of reach of children and pets
  • Do not use expired medication

Special Advice for Patients

  • Regular blood tests for lipids and thyroid levels are required
  • Avoid excessive sunlight exposure; use sun protection
  • Maintain a healthy diet to manage cholesterol levels
  • Report symptoms like fatigue, weight changes, or skin irritation

Why Choose Onco India International?

At Onco India International, we are committed to delivering high-quality, affordable, and globally trusted oncology medicines. Our Bexarotene 75 mg Capsules are manufactured under strict quality standards to ensure safety, effectiveness, and reliability in cancer care.