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Captopril Tablets

Product/Composition Captopril Tablets
Strength 12.5mg, 25mg
Form Tablets
Production Capacity 10 Million Tablet/Month
Packaging 10 X 10 Tablets / Box
Therapeutic use Cardiovascular
Package Insert/Leaflet Available upon request

INQUIRE ABOUT Captopril Tablets

Captopril Tablets

Category: ACE inhibitor (Angiotensin-Converting Enzyme Inhibitor)
Form: Oral tablets

Uses:

  • Treatment of high blood pressure (hypertension).

  • Management of heart failure, often in combination with other drugs.

  • Improves survival after heart attack (myocardial infarction).

  • Slows progression of diabetic kidney disease and other chronic kidney disorders.

Mechanism of Action:

  • Captopril blocks the angiotensin-converting enzyme (ACE).

  • This prevents the conversion of angiotensin I to angiotensin II, a strong vasoconstrictor.

  • Leads to blood vessel relaxation, reduced blood pressure, and decreased workload on the heart.

  • Also reduces aldosterone secretion, lowering sodium and water retention.

Administration:

  • Taken orally, usually 2–3 times daily (shorter duration compared to newer ACE inhibitors).

  • Can be taken with or without food, but consistency is advised.

Side Effects:

  • Common: dizziness, cough (dry, persistent), fatigue, headache.

  • Cardiovascular: low blood pressure, especially after first dose.

  • Metabolic: high potassium levels (hyperkalemia).

  • Renal: changes in kidney function, especially in patients with kidney disease.

  • Other: rash, taste changes (metallic or loss of taste), rarely angioedema (serious swelling of face, lips, throat).

Precautions:

  • Not safe during pregnancy (can cause serious fetal harm) or breastfeeding.

  • Monitor kidney function and potassium levels regularly.

  • Use cautiously in patients with kidney impairment, dehydration, or low blood pressure.

  • Avoid combination with potassium supplements or potassium-sparing diuretics unless strictly supervised.

Summary:
Captopril Tablets are an ACE inhibitor used to treat hypertension, heart failure, post-heart attack recovery, and diabetic kidney disease. By blocking angiotensin II production, it lowers blood pressure, reduces fluid overload, and eases strain on the heart. Though effective, it requires frequent dosing and monitoring and may cause cough, high potassium, or rare but serious angioedema.