Cefpodoxime Proxetil 200 mg Tablets

Category: Third-generation cephalosporin antibiotic
Form: Oral tablets

Uses:

• Treatment of bacterial infections caused by susceptible organisms.

• Common indications include:

  • Respiratory tract infections (bronchitis, pneumonia, sinusitis)

  • Ear infections (otitis media)

  • Throat infections (pharyngitis/tonsillitis)

  • Urinary tract infections (UTIs)

  • Skin and soft tissue infections

Mechanism of Action:

• Cefpodoxime Proxetil is a prodrug that is converted to cefpodoxime in the body.

• Cefpodoxime works by inhibiting bacterial cell wall synthesis, causing bacterial cell death.

• Effective mainly against Gram-negative bacteria and some Gram-positive bacteria.

Administration:

• Taken orally, usually once or twice daily depending on infection severity and patient condition.

• Can be taken with or without food, but taking it with food may improve absorption.

• Complete the full course to prevent recurrence and bacterial resistance.

Side Effects:

• Common: nausea, vomiting, diarrhea, abdominal discomfort, mild skin rash.

• Rare but serious: allergic reactions, severe diarrhea due to Clostridium difficile infection, liver enzyme elevation.

Precautions:

• Avoid in patients with known allergy to cephalosporins.

• Use cautiously in kidney or liver impairment; dose adjustment may be needed.

• Maintain hydration and report any severe gastrointestinal symptoms or allergic reactions.

• Complete the entire prescribed course even if symptoms improve early.

Summary:
Cefpodoxime Proxetil 200 mg Tablets are an oral third-generation cephalosporin antibiotic used to treat a variety of bacterial infections, including respiratory, urinary, ear, throat, and skin infections. The prodrug form is converted to active cefpodoxime in the body. Common side effects include gastrointestinal upset and mild rash, while serious allergic reactions are rare but require monitoring.