Cyproterone Tablets

Category: Anti-androgen / Hormonal agent
Form: Oral tablets

Uses:

• Treatment of androgen-dependent conditions in men, such as:

  • Prostate cancer

  • Severe hypersexuality or sexual deviations

• Management of hirsutism (excessive hair growth) and acne in women due to androgen excess.

• Sometimes used in transgender hormone therapy to reduce male hormone effects.

Mechanism of Action:

• Cyproterone is an anti-androgen that blocks androgen receptors, preventing testosterone and other androgens from exerting their effects.

• In women, it also has progestogenic activity, which suppresses gonadotropin secretion and reduces androgen production from ovaries.

Administration:

• Taken orally, usually once or twice daily, depending on condition and doctor’s prescription.

• Dose is individualized based on age, sex, and clinical condition.

Side Effects:

• Common: fatigue, weight gain, breast tenderness or enlargement, decreased libido.

• Other: mood changes, nausea, headache, hot flashes.

• Rare but serious:

  • Liver toxicity

  • Blood clots (deep vein thrombosis or pulmonary embolism)

  • Severe allergic reactions

Precautions:

• Regular liver function monitoring is recommended.

• Avoid use in pregnancy (can cause fetal harm) and breastfeeding.

• Use cautiously in patients with history of blood clots or liver disease.

• May interact with other hormonal therapies or drugs affecting liver metabolism.

Summary:
Cyproterone Tablets are an anti-androgen and progestogenic agent used to treat prostate cancer, androgen-related disorders in men, and hirsutism or acne in women. They work by blocking androgen receptors and suppressing androgen production. Common side effects include fatigue, weight gain, and breast changes, while serious risks such as liver toxicity and blood clots require careful medical monitoring.