Deflazacort Tablets are a type of medicine classified as a corticosteroid. They are used to reduce inflammation, suppress the immune system, and manage various conditions where corticosteroid therapy is beneficial.

Here are the key details:

• Composition: Each tablet contains Deflazacort as the active ingredient, available in strengths such as 6 mg, 18 mg, 30 mg, etc.

• Dosage Form: Oral tablets, usually film-coated.

• Mode of Action: Deflazacort works by mimicking natural glucocorticoid hormones in the body. It reduces inflammation, modulates the immune response, and decreases the activity of substances in the body that cause swelling and allergic reactions.

• Uses:

  • Duchenne Muscular Dystrophy (DMD) – slows disease progression and helps maintain muscle strength.

  • Autoimmune diseases such as lupus, rheumatoid arthritis, and multiple sclerosis.

  • Inflammatory conditions like asthma, allergies, and certain skin disorders.

  • Organ transplantation (to prevent rejection).

  • Certain blood disorders.

• Treatment Goal: To control symptoms, reduce inflammation, and improve quality of life in chronic or acute conditions.

• Side Effects:

  • Common: weight gain, increased appetite, mood changes, insomnia, indigestion.

  • Long-term: osteoporosis, growth suppression in children, high blood pressure, diabetes, cataracts, increased infection risk.

• Precautions:

  • Should not be stopped suddenly after long-term use; requires gradual tapering.

  • Monitoring is needed for blood sugar, blood pressure, and bone health.

  • Caution in patients with active infections, peptic ulcer, or uncontrolled diabetes.

  • Prolonged use can suppress natural cortisol production.