Divalproex Sodium Tablets are a medicine primarily used to treat seizure disorders, mood disorders, and migraine prevention. It is a form of valproate that delivers both valproic acid and sodium valproate.

Here are the key details:

• Composition: Each tablet contains Divalproex Sodium as the active ingredient, available in strengths like 125 mg, 250 mg, and 500 mg.

• Dosage Form: Oral tablets, including immediate-release and extended-release (ER) formulations.

• Mode of Action:

  • Increases levels of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits excessive brain activity.

  • Stabilizes electrical activity in the brain, reducing seizures.

  • Helps regulate mood in bipolar disorder and can prevent migraine headaches.

• Uses:

  • Epilepsy: treatment of partial, generalized, and absence seizures.

  • Bipolar disorder: management of manic or mixed episodes.

  • Migraine prophylaxis: to reduce the frequency of migraine attacks.

• Treatment Goal: To control seizures, stabilize mood, and prevent migraines.

• Side Effects:

  • Common: nausea, vomiting, diarrhea, dizziness, drowsiness, tremor, weight gain.

  • Serious: liver toxicity, pancreatitis, low platelet count, hair loss, or birth defects if used during pregnancy.

• Precautions:

  • Liver function and blood counts should be monitored regularly.

  • Not recommended in severe liver disease or urea cycle disorders.

  • Can interact with other medicines like anticoagulants, other anticonvulsants, and certain antibiotics.

  • Women of childbearing age should use effective contraception due to risk of birth defects.

  • Avoid sudden discontinuation; dose should be tapered under medical supervision.

👉 Divalproex Sodium is widely used because it combines seizure control and mood stabilization in a single medicine, but careful monitoring is essential due to potential liver and blood-related risks.