Domperidone Tablets are a medicine used to improve gastrointestinal motility and relieve symptoms related to delayed stomach emptying.

Here are the key details:

• Composition: Each tablet contains Domperidone as the active ingredient, commonly in strengths such as 10 mg or 20 mg.

• Dosage Form: Oral tablets, typically taken before meals or as prescribed by a doctor.

• Mode of Action:

  • Domperidone works as a dopamine D2 receptor antagonist.

  • It increases the movement of the stomach and intestines, helping food pass more quickly.

  • It also blocks dopamine receptors in the brain that trigger nausea and vomiting.

• Uses:

  • Relief of nausea and vomiting caused by various conditions or medications.

  • Management of gastroparesis (delayed stomach emptying), especially in diabetic patients.

  • Sometimes used to increase milk production in breastfeeding women (under medical supervision).

• Treatment Goal: To reduce nausea, vomiting, bloating, and other symptoms of slow gastric emptying, and to improve digestive comfort.

• Side Effects:

  • Common: dry mouth, abdominal cramps, headache, dizziness.

  • Less common: diarrhea, rash, breast tenderness, increased prolactin levels.

  • Rare: irregular heart rhythms (QT prolongation), especially at high doses or in patients with heart disease.

• Precautions:

  • Should be used with caution in patients with heart conditions or low potassium/magnesium levels.

  • Avoid high doses for long periods unless monitored by a doctor.

  • May interact with certain medicines that affect heart rhythm or liver metabolism.

  • Not recommended during late pregnancy or in newborns without medical supervision.

👉 Domperidone is effective for nausea, vomiting, and gastric motility issues, but care is needed in patients with heart risk factors due to its potential cardiac effects.