What is Estramustine 140 mg Capsule?

Estramustine 140 mg Capsule is an anticancer medication used primarily in the treatment of advanced prostate cancer. It is a unique combination of an estrogen derivative and a nitrogen mustard (alkylating agent), designed to interfere with cancer cell growth and division.

This medicine is especially used in patients with metastatic or progressive prostate cancer, where it helps slow the spread of the disease and manage symptoms effectively.

Description

Estramustine 140 mg Capsule is an oral chemotherapy drug that targets prostate cancer cells through multiple mechanisms. It disrupts the structure of microtubules within cancer cells, which are essential for cell division, thereby preventing tumor growth.

The capsule form allows convenient administration and is typically prescribed as part of a broader cancer treatment plan under strict medical supervision.

Uses of Estramustine 140 mg Capsule

• Treatment of advanced prostate cancer
• Management of metastatic prostate cancer
• Used in hormone-resistant prostate cancer cases
• Helps control cancer progression and related symptoms

Indications

• Indicated for adult male patients with progressive prostate cancer
• Used when other hormone therapies are ineffective
• Prescribed under the supervision of an oncologist
• Dosage depends on the patient’s condition and response to treatment

Benefits

• Targets cancer cells through dual mechanism (hormonal and cytotoxic)
• Helps slow tumor growth and spread
• Provides symptom relief in advanced cancer stages
• Oral capsule form ensures ease of use
• Can be combined with other cancer treatments

Drug Interactions

Estramustine may interact with the following medications:

• Calcium-containing products (milk, supplements)
• Anticoagulants like warfarin
• Other chemotherapy drugs
• Estrogen-containing medications
• Vaccines (especially live vaccines)

Always inform your doctor about all medications, supplements, or herbal products before starting treatment.

How Estramustine Works

• Disrupts microtubule formation in cancer cells
• Inhibits cell division and tumor growth
• Provides estrogenic activity that affects prostate cancer cells
• Leads to cancer cell death and slows disease progression

Warnings & Precautions

• May increase risk of blood clots—monitor for symptoms like swelling or chest pain
• Use cautiously in patients with heart disease or hypertension
• Can cause nausea, vomiting, and breast tenderness
• Avoid use in patients with a history of thromboembolic disorders
• Not recommended during pregnancy or for use by women

General Instructions

• Take the capsule exactly as prescribed by your doctor
• Swallow whole with water; do not crush or chew
• Take on an empty stomach (1 hour before or 2 hours after meals)
• Avoid dairy products close to dosing time
• Do not stop treatment without medical advice

Storage Information

• Store in a cool, dry place away from heat and moisture
• Keep in original packaging
• Keep out of reach of children and pets
• Do not use expired medication

Special Advice for Patients

• Regular monitoring and follow-up are essential
• Maintain a healthy lifestyle and balanced diet
• Report symptoms like swelling, shortness of breath, or severe pain immediately
• Avoid calcium-rich foods near dosing time

Why Choose Onco India International?

At Onco India International, we are committed to delivering high-quality, affordable, and globally trusted oncology medicines. Our Estramustine 140 mg Capsules are manufactured under strict quality standards to ensure safety, effectiveness, and reliability in cancer treatment.