Estraval Depot Injection

Product/Composition Estradiol Valerate
Strength 10mg
Form Ampoule
Therapeutic use Hormones & Steroids
Package Insert/Leaflet Available upon request

Estraval Depot Injection

What is Estraval Depot Injection?

Estraval Depot Injection is a form of hormone replacement therapy (HRT) primarily prescribed to treat conditions related to estrogen deficiency.

It is commonly recommended for postmenopausal symptoms, hormonal imbalances, and other health conditions that require estrogen supplementation.

Manufacturer

Onco India International is the trusted manufacturer of Estraval Depot Injection, ensuring high-quality, safe, and authentic medicines. The company strictly adheres to international compliance and quality standards, providing reliable pharmaceutical solutions worldwide.

Uses of Estraval Depot Injection

Estraval Depot Injection is widely used in estrogen replacement therapy. Its main uses include:

  • Relief from postmenopausal symptoms such as vaginal dryness, hot flashes, and mood swings.

  • Prevention of osteoporosis in postmenopausal women by maintaining bone density and reducing fracture risk.

  • Treatment of hypogonadism and primary ovarian failure.

  • Support in cases requiring hormonal balance and estrogen supplementation.

Composition of Estraval Depot Injection

The injection contains:

  • Estradiol Valerate – a synthetic form of estrogen that is bioidentical to natural estrogen produced in the body.

How Does Estraval Depot Injection Work?

Once administered, Estraval Depot Injection converts into estradiol, the active form of estrogen. It binds to estrogen receptors in different tissues, regulating essential physiological processes such as:

  • Maintaining bone density.

  • Supporting reproductive tissues (uterus, vagina).

  • Regulating cholesterol and improving vascular health.

  • Enhancing skin elasticity and overall skin and hair health.

Administration Method

  • Estraval Depot Injection is given intramuscularly under the supervision of a qualified healthcare provider.

  • The frequency of administration depends on the patient’s condition and severity.

  • Always consult a healthcare specialist for the correct dosage and monitoring.

Benefits of Estraval Depot Injection

  • Relief from menopausal symptoms – helps reduce hot flashes, vaginal dryness, and sleep disturbances.

  • Osteoporosis prevention – supports bone density and reduces fracture risks.

  • Hormonal support – restores balance in hypogonadism and ovarian failure.

  • Cardiovascular benefits – improves lipid profiles, increases HDL, and supports vascular health.

  • Skin and hair improvement – promotes elasticity and scalp circulation for healthier appearance.

Dosage

  • Typically administered every 2–4 weeks, depending on individual health requirements.

  • Dosage adjustments are made by the doctor after careful evaluation.

  • Regular medical monitoring is recommended.

Missed Dose

If you miss a dose:

  • Contact your healthcare provider immediately for advice.

  • Do not double the dose on your own, as it may cause adverse effects.

Substitutes

In certain cases, alternatives may include:

  • Mifepristone Tablets

  • Norethisterone Tablets

  • Oxandrolone Tablets

  • Oxymetholone Tablets

  • Prednisolone Tablets

Overdose Risks & Side Effects

Excessive use of Estraval Depot Injection may cause:

Common Side Effects:

  • Nausea, headache, mood swings, spotting, weight changes, facial flushing.

Serious Side Effects:

  • Blood clots

  • Severe allergic reactions

  • Liver function abnormalities

  • Risk of hormone-sensitive cancers (with long-term use)

When Not to Use Estraval Depot Injection

Avoid use if:

  • Pregnant or breastfeeding.

  • You have or had hormone-sensitive cancer.

  • You suffer from blood clots or have a history of thrombosis.

  • You have unexplained vaginal bleeding.

  • You have severe heart or liver conditions.

Warnings & Precautions

  • Regular medical checkups (mammograms, pelvic exams) are recommended during therapy.

  • Inform your doctor about any other existing conditions such as heart disease, diabetes, asthma, or hypertension.

  • Avoid smoking, alcohol, and recreational drugs during treatment.

  • Inform your doctor about any other medications being used to avoid drug interactions.

Storage Guidelines

  • Store at 15–30°C (room temperature).

  • Keep away from heat, moisture, and direct light.

  • Keep out of children’s reach.

 With Onco India International’s commitment to safety and quality, Estraval Depot Injection is a trusted solution for effective estrogen replacement therapy.