Exemestane Tablets are a medicine classified as an aromatase inhibitor, primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women.

Here are the key details:

• Composition: Each tablet contains Exemestane as the active ingredient, commonly in a 25 mg strength.

• Dosage Form: Oral tablets, usually taken once daily after a meal, as prescribed by a doctor.

• Mode of Action:

  • Exemestane inhibits the aromatase enzyme, which is responsible for converting androgens into estrogen.

  • By lowering estrogen levels in the body, it reduces the growth stimulus for estrogen-dependent breast cancer cells.

• Uses:

  • Hormone receptor-positive breast cancer – often used after surgery, radiation, or chemotherapy to prevent recurrence.

  • May be used in cases where other hormonal therapies (like tamoxifen) are no longer effective.

• Treatment Goal: To reduce estrogen levels, slow cancer growth, and prevent recurrence in estrogen-sensitive breast cancers.

• Side Effects:

  • Common: hot flashes, joint pain, fatigue, headache, nausea, increased sweating.

  • Less common/serious: bone thinning (osteoporosis), fractures, high cholesterol, liver function changes, mood changes.

• Precautions:

  • Regular monitoring of bone density and cholesterol levels is recommended during long-term use.

  • Not recommended during pregnancy or breastfeeding.

  • Patients may need calcium and vitamin D supplementation to support bone health.

  • Should be taken exactly as prescribed, usually for several years depending on the treatment plan.

👉 Exemestane is effective in postmenopausal women with hormone-sensitive breast cancer because it specifically targets estrogen production, reducing the risk of cancer recurrence.