Fenofibrate Tablets are a medicine used to manage abnormal blood lipid levels, particularly high cholesterol and triglycerides. They belong to a class of drugs called fibrates.

Here are the key details:

• Composition: Each tablet contains Fenofibrate as the active ingredient, commonly in strengths such as 67 mg, 145 mg, or 200 mg.

• Dosage Form: Oral tablets, usually taken once daily with food, as prescribed by a doctor.

• Mode of Action:

  • Fenofibrate activates peroxisome proliferator-activated receptor alpha (PPARα).

  • This increases the breakdown of triglycerides and promotes the removal of LDL (“bad”) cholesterol while raising HDL (“good”) cholesterol.

• Uses:

  • Hypertriglyceridemia – high triglyceride levels.

  • Mixed dyslipidemia – high cholesterol and triglycerides.

  • Often used when diet and lifestyle changes alone are insufficient to control lipid levels.

• Treatment Goal: To lower triglycerides, reduce LDL cholesterol, increase HDL cholesterol, and decrease the risk of cardiovascular disease.

• Side Effects:

  • Common: stomach upset, nausea, headache, muscle pain.

  • Less common/serious: liver function changes, gallstones, muscle damage (myopathy or rhabdomyolysis, especially if combined with statins), allergic reactions.

• Precautions:

  • Regular monitoring of liver function, kidney function, and lipid levels is recommended.

  • Use with caution in patients with liver, kidney, or gallbladder disease.

  • Stay well hydrated to reduce risk of kidney problems.

  • Should be used in combination with a low-fat diet and healthy lifestyle for optimal results.

  • Inform the doctor about any history of muscle disorders or statin use.

👉 Fenofibrate is effective for controlling high triglycerides and certain cholesterol abnormalities, helping reduce cardiovascular risk when used alongside diet and lifestyle changes.