Fluorouracil Cream USP

Product/Composition Fluorouracil Cream USP
Strength 5%
Form Cream
Production Capacity 1 Million Cream / Month
Packaging 10gm
Therapeutic use Skin Care, Dermatology
Package Insert/Leaflet Available upon request

Fluorouracil Cream

What is Fluorouracil Cream?

Fluorouracil Cream is a topical medication used to treat specific skin cancers and precancerous skin lesions. It works by removing abnormal skin cells, helping your skin appear clearer and healthier. This cream is effective in preventing skin conditions that could develop into cancer.

Overview

Fluorouracil cream, also known as 5-FU, is applied directly to affected areas of the skin to manage precancerous lesions and early-stage skin cancers. It is important to follow the recommended dosage for safe and effective treatment.

Description

This cream contains fluorouracil, a potent medication in a white or off-white topical form. Treated skin may appear red, flaky, or itchy, which indicates the treatment is working.

Uses / Indications

Fluorouracil cream is primarily prescribed for:

  • Actinic Keratosis: Rough, scaly patches of skin often caused by sun exposure.

  • Early Skin Cancers: Including basal cell carcinoma and other precancerous lesions.

Benefits

  • Eliminates cells that may become cancerous, reducing skin cancer risk.

  • Prevents the progression of precancerous lesions.

  • Improves the appearance and texture of rough or crusty skin.

  • Suitable when other treatments are less effective, especially for early-stage skin cancer.

Side Effects

Common side effects may include:

  • Burning sensation

  • Swelling

  • Dryness

  • Itching

  • Redness

Severe reactions are rare but should be reported to your doctor immediately.

How It Works

Fluorouracil cream blocks the DNA synthesis of rapidly dividing cells, causing the death of abnormal or precancerous skin cells. This mechanism helps clear actinic keratoses and early-stage skin cancers.

Directions for Use

  1. Clean and dry the affected area before applying the cream.

  2. Use gloves or a cotton swab to apply a thin layer to the affected skin.

  3. Avoid contact with eyes, nose, and mouth.

  4. Complete the full course as prescribed by your doctor.

When Not to Use

Avoid using Fluorouracil cream if:

  • You are allergic to fluorouracil or any ingredient in the cream.

  • You are pregnant or planning pregnancy.

  • You have a deficiency in the DPD enzyme.

  • The treatment area is open, sore, or severely irritated.

Drug Interactions

Safe with: Herbal products, vitamins/minerals, thiamine, levamisole, rolapitant, methotrexate, cimetidine, warfarin.
Avoid: Brivudine, tegafur, and live vaccines (typhoid, measles, mumps, rubella, varicella, yellow fever).

Safety Advice & Precautions

  • Inform your doctor about all medications, supplements, and allergies before using.

  • Avoid sunlamps, tanning beds, and prolonged sunlight exposure, as treated skin is highly sensitive.

  • Keep pets and children away from the treated area.

  • Pregnant or breastfeeding women should consult their doctor before use.

Dietary & Lifestyle Recommendations

  • Use sunscreen and protective clothing when outdoors.

  • Maintain normal diet; alcohol may be avoided unless approved by your doctor.

Storage

  • Store in original packaging with the lid tightly closed.

  • Keep at 20°C to 25°C (68°F–77°F) in a cool, dry place away from children, pets, heat, and moisture.

Buy Fluorouracil Cream

Onco India International is a trusted manufacturer, supplier, and exporter of Fluorouracil Cream. For genuine products, bulk orders, or distribution inquiries, contact Onco India International directly.