Gefitinib Tablets are a medicine used to treat certain types of cancer, primarily non-small cell lung cancer (NSCLC) with specific genetic mutations. They belong to a class of drugs called tyrosine kinase inhibitors (TKIs).

Here are the key details:

• Composition: Each tablet contains Gefitinib, commonly in a 250 mg strength.

• Dosage Form: Oral tablets, usually taken once daily, with or without food, as prescribed by a doctor.

• Mode of Action:

  • Gefitinib specifically blocks the epidermal growth factor receptor (EGFR) tyrosine kinase, which is involved in the growth and division of cancer cells.

  • By inhibiting EGFR, it slows down cancer cell growth, division, and spread.

• Uses:

  • Non-small cell lung cancer (NSCLC) – especially in patients with EGFR gene mutations.

  • Sometimes used in other cancers under medical guidance if the tumor expresses EGFR.

• Treatment Goal: To slow cancer progression, reduce tumor size, and improve survival and quality of life in patients with EGFR-positive cancers.

• Side Effects:

  • Common: diarrhea, skin rash, acne, dry skin, nausea, fatigue.

  • Less common/serious: liver function changes, interstitial lung disease (breathing problems), eye disorders, severe skin reactions.

• Precautions:

  • Regular monitoring of liver function, lung function, and overall health is required.

  • Not recommended during pregnancy or breastfeeding.

  • Avoid combining with certain medications that affect liver enzymes, as it may alter drug levels.

  • Take the tablet at the same time daily and do not crush or chew unless instructed.

👉 Gefitinib is effective because it targets cancer cells with EGFR mutations specifically, making it a form of targeted therapy that can be more effective and have fewer systemic effects than traditional chemotherapy.