Glibenclamide Tablets are a medicine used to treat type 2 diabetes mellitus. They belong to a class of drugs called sulfonylureas, which help lower blood sugar levels.

Here are the key details:

• Composition: Each tablet contains Glibenclamide, commonly in strengths such as 2.5 mg or 5 mg.

• Dosage Form: Oral tablets, usually taken once or twice daily with meals, as prescribed by a doctor.

• Mode of Action:

  • Glibenclamide stimulates the pancreas to release more insulin, which helps lower blood glucose levels.

  • It works best in patients whose pancreas still produces some insulin.

• Uses:

  • Type 2 diabetes mellitus – to control high blood sugar when diet and lifestyle measures alone are insufficient.

  • Helps reduce both fasting and post-meal blood glucose levels.

• Treatment Goal: To maintain blood sugar within target levels and prevent diabetes-related complications.

• Side Effects:

  • Common: hypoglycemia (low blood sugar), nausea, vomiting, mild gastrointestinal upset, weight gain.

  • Less common/serious: allergic reactions, liver function changes, skin rashes, blood disorders (rare).

• Precautions:

  • Regular blood sugar monitoring is important to avoid hypoglycemia.

  • Take with meals to reduce the risk of low blood sugar.

  • Use caution in patients with liver, kidney, or heart problems.

  • Not recommended during pregnancy or breastfeeding unless prescribed.

  • Avoid excessive alcohol, as it may increase hypoglycemia risk.

  • Inform the doctor about other medications to prevent interactions.

👉 Glibenclamide is effective for stimulating insulin release and controlling blood sugar in type 2 diabetes, especially when the pancreas can still produce insulin.