Hydroquinone, Tretinoin, and Mometasone Cream

What is Hydroquinone, Tretinoin, and Mometasone Cream?

Hydroquinone, Tretinoin, and Mometasone Cream is a dermatological formulation designed to manage hyperpigmentation, including melasma, dark spots, and post-inflammatory hyperpigmentation. The cream contains three active ingredients that work synergistically to lighten the skin, enhance cell renewal, and reduce inflammation. Dermatologists recommend it for short-term use under strict medical supervision.

Uses

• Management of melasma (hyperpigmented patches caused by sun exposure or hormonal changes)

• Treatment of post-inflammatory hyperpigmentation (PIH)

• Minimization of freckles, age spots, and sun-induced pigmentation

• Lightening of irregular skin tone and discoloration

• Treatment of hyperpigmentation related to acne

• Reduction of inflammation that contributes to pigmentation

Benefits

• Reduces hyperpigmentation by inhibiting melanin production

• Promotes faster skin renewal through exfoliation and increased cell turnover

• Reduces inflammation and redness caused by irritation or skin conditions

• Improves skin texture and tone for a smoother, more luminous appearance

• Prevents further darkening when combined with sun protection

How It Works

• Hydroquinone blocks tyrosinase, the enzyme responsible for melanin production, eliminating dark spots and uneven pigmentation.

• Tretinoin (Vitamin A derivative) accelerates skin cell turnover, unclogs pores, and enhances the efficacy of other ingredients.

• Mometasone (corticosteroid) reduces redness, swelling, and itching by calming the immune response and inhibiting inflammatory mediators.

Together, these ingredients address melasma, dark spots, and inflammatory skin conditions, resulting in healthier, even-toned skin.

Directions for Use

1. Cleanse the skin with a gentle, non-irritating cleanser and pat dry.

2. Apply a small layer of the cream to the affected area once daily, preferably at night.

3. Avoid applying on unaffected skin to prevent unnecessary lightening.

4. Use a broad-spectrum sunscreen (SPF 30 or higher) during the day to prevent further discoloration.

5. Avoid excessive rubbing or manipulation of the cream on the skin.

When Not to Use

• Allergic Reactions – Avoid if allergic to Hydroquinone, Tretinoin, Mometasone, or any other component.

• Skin Infections – Do not use on bacterial, fungal, or viral infections such as herpes, chickenpox, or impetigo.

• Open Wounds or Broken Skin – Avoid cuts, burns, or sores as it may irritate or worsen the area.

• Pregnancy & Breastfeeding – Use only under doctor’s supervision due to potential risks.

• Photosensitivity – May worsen skin sensitivity to sunlight.

Drug Interactions

Safe to Use With:

• Non-comedogenic moisturizers for sensitive skin

• Gentle cleansers without harsh chemicals

• Broad-spectrum sunscreens

To Avoid:

• Other retinoids (adapalene, isotretinoin, retinol serums)

• Benzoyl peroxide, salicylic acid, and other corticosteroids

• Chemical peels, laser treatments, or microdermabrasion during treatment

Safety Advice

• Initial side effects may include skin irritation, redness, and peeling; these often subside with continued use.

• Long-term use of Hydroquinone may cause ochronosis (permanent skin darkening).

• Abrupt discontinuation of corticosteroids can cause dependency and worsening pigmentation.

• Apply pea-sized amounts and only at night to avoid excessive irritation.

• Conduct a patch test before applying to the entire face.

General Instructions

• Follow the prescribed dosage; avoid self-medication.

• Store in a cool, dry place, away from direct sunlight.

• Do not share the cream with others.

• Avoid applying to large skin areas without medical consultation.

Dietary & Lifestyle Recommendations

• Consume a balanced diet rich in vitamins, antioxidants, and essential fatty acids (citrus fruits, nuts, leafy greens).

• Stay hydrated to prevent dry, irritated skin.

• Limit intake of sugar, dairy, alcohol, and caffeine if they aggravate skin problems.

• Use gentle cleansers, moisturize regularly, and wear sunscreen daily.

• Practice stress-relieving activities like yoga, meditation, or exercise.

• Ensure adequate sleep for optimal skin repair and renewal.

Comparison with Other Treatments

• Azelaic Acid – Milder option for sensitive skin.

• Kojic Acid – Natural skin brightener with slower results.

• Niacinamide – Improves skin tone moderately; slower than Hydroquinone.

• Chemical Peels & Laser Treatments – Faster results but higher cost and downtime.

Precautions / What Not to Do

• Avoid using on broken, irritated, or infected skin.

• Limit sun exposure and always use sunscreen to prevent sunburn.

• Do not use for longer than prescribed; long-term use may thin skin or worsen pigmentation.

• Avoid harsh skincare products (alcohol-based toners, scrubs, strong soaps).

• Do not share the cream with others.

• Keep away from eyes, mouth, and nasal membranes.

• If irritation, redness, or allergic reactions occur, discontinue use and consult a doctor immediately.

Purchase

Onco India International is a trusted manufacturer, supplier, and exporter of Hydroquinone, Tretinoin, and Mometasone Cream. For authentic products, bulk orders, or distribution inquiries, contact Onco India International directly.