Ibuprofen and Paracetamol Tablets are a fixed-dose combination medicine that provides pain relief and fever reduction by combining two well-known drugs:

• Ibuprofen – a non-steroidal anti-inflammatory drug (NSAID).

• Paracetamol (Acetaminophen) – an analgesic and antipyretic.

Key Details:

• Composition: Each tablet usually contains Ibuprofen (commonly 200–400 mg) and Paracetamol (commonly 325–500 mg).

• Dosage Form: Oral tablets.

How It Works:

• Ibuprofen: Reduces pain, inflammation, and swelling by inhibiting prostaglandin production.

• Paracetamol: Works mainly in the brain to reduce fever and relieve pain.

• Together, they provide stronger and faster pain relief than either drug alone.

Uses:

• Headache and migraine.

• Toothache or dental pain.

• Musculoskeletal pain (back pain, joint pain, sprains, strains).

• Menstrual cramps.

• Fever associated with infections or inflammation.

• Post-surgical or post-vaccination pain and fever.

Side Effects:

• Common: nausea, indigestion, abdominal discomfort.

• Less common: dizziness, rash, diarrhea.

• Rare/serious: stomach ulcers or bleeding (from ibuprofen), liver damage (from paracetamol overdose), kidney problems (with long-term use).

Precautions:

• Should be taken with food or milk to reduce stomach irritation.

• Avoid alcohol, as it increases the risk of liver damage (from paracetamol) and stomach irritation/bleeding (from ibuprofen).

• Use with caution in patients with liver disease, kidney disease, stomach ulcers, or heart problems.

• Should not exceed the maximum daily dose of Paracetamol (4 g/day) or Ibuprofen (1.2–2.4 g/day for adults, depending on prescription).

• Not recommended in late pregnancy due to ibuprofen’s effects on the baby’s heart and kidneys.

Treatment Goal:

To provide quick, effective, and balanced relief from pain, inflammation, and fever by combining the strengths of both medicines.