Isosorbide Dinitrate Tablets are a prescription medicine that belongs to the group of drugs called nitrates, mainly used for heart-related conditions.

Here are the key details:

• Main Use: Commonly prescribed for the prevention and treatment of chest pain (angina pectoris) due to coronary artery disease. They may also be used in certain cases of heart failure.

• How It Works: Isosorbide dinitrate relaxes and widens blood vessels by releasing nitric oxide. This reduces the workload on the heart, improves blood and oxygen supply, and helps prevent chest pain.

• Administration: Taken orally, usually two to three times daily, as directed by the doctor. In some cases, dosing schedules are adjusted to avoid tolerance (reduced effectiveness if taken continuously without breaks).

• Common Side Effects: Headache, dizziness, flushing, lightheadedness (especially when standing up suddenly), and low blood pressure.

• Serious Concerns: Rarely, it may cause severe hypotension (very low blood pressure), rapid heartbeat, or allergic reactions. Medical help may be required in such cases.

• Precautions:

  • Should not be combined with certain medicines for erectile dysfunction (like sildenafil, tadalafil, vardenafil) due to risk of dangerous blood pressure drop.

  • Caution in patients with very low blood pressure, anemia, glaucoma, or recent head injury.

  • Not recommended during acute heart attack without strict medical supervision.

• Storage: Usually stored at room temperature, protected from moisture and direct sunlight.