Lamivudine, Nevirapine, and Stavudine Tablets are a combination antiviral medicine used to manage HIV infection. This combination brings together three drugs that work in different ways to control the virus.

Here are the key details:

• Composition:

  • Lamivudine – a nucleoside reverse transcriptase inhibitor (NRTI) that prevents the virus from multiplying.

  • Nevirapine – a non-nucleoside reverse transcriptase inhibitor (NNRTI) that blocks an enzyme the virus needs to replicate.

  • Stavudine – another NRTI that interferes with viral replication.

• Main Use: Prescribed for managing HIV infection. The combination helps reduce the viral load in the body, improve immune function, and slow disease progression.

• How It Works: Each drug targets the HIV virus in a slightly different way, preventing it from multiplying and allowing the immune system to recover and function more effectively.

• Administration: Taken orally, usually twice daily, as directed by the doctor. It is important to take the medicine at the same times each day and not skip doses.

• Common Side Effects: Nausea, vomiting, diarrhea, headache, fatigue, dizziness, or mild skin rash.

• Serious Concerns: Rarely, it may cause liver problems, severe skin reactions, lactic acidosis (buildup of lactic acid), peripheral neuropathy (nerve problems), or worsening of other infections.

• Precautions:

  • Requires regular monitoring of liver and kidney function, as well as blood counts.

  • Not to be stopped suddenly without doctor supervision to prevent viral resistance.

  • Patients should inform the doctor of any other medications or supplements being taken due to potential interactions.

• Storage: Store at room temperature, away from moisture, heat, and direct sunlight.