Lomustine Capsules

What is Lomustine?

Lomustine is a chemotherapy medicine primarily used to treat brain tumors (including glioblastoma) and Hodgkin’s lymphoma. It belongs to a class of drugs known as nitrosoureas, which work by damaging the DNA of cancer cells, thereby stopping them from growing and dividing.

A major advantage of Lomustine is its ability to cross the blood-brain barrier, making it especially effective for brain cancer treatment. It is often combined with other therapies to improve outcomes. However, since it has significant effects on bone marrow, regular monitoring is essential during treatment.

Uses of Lomustine Capsules

Primary Uses

• Treatment of brain cancers, such as glioblastoma multiforme.

• Management of Hodgkin’s lymphoma that has not responded to other treatments.

Indications

• High-grade gliomas.

• Relapsed or refractory Hodgkin’s lymphoma.

• Sometimes used for cancers of the lungs and stomach.

Benefits of Lomustine

Effective Against Resistant Cancers – Works in cases where other treatments have failed.
Convenient Oral Administration – Available in capsule form, making home use possible.
Crosses the Blood-Brain Barrier – Directly targets brain tumors.
Long-Lasting Effects – Dosed less frequently compared to many chemotherapy drugs.
Combination Therapy Potential – Enhances results when paired with radiation or other chemotherapy drugs.

How Lomustine Works

Lomustine damages the DNA of cancer cells by creating breaks in their structure. This prevents them from dividing and growing, eventually leading to their death. Unlike some chemotherapy drugs, Lomustine remains active in the body for a longer period, continuing to target cancer cells after administration.

Dosage Guidelines

• Route of Administration: Oral (capsules, swallowed whole with water).

• Typical Schedule: Once every six weeks.

• Standard Dose: Around 130 mg/m² every six weeks (adjusted by body weight, health condition, and response).

Do Not Use If:

• You have severe bone marrow suppression.

• You are pregnant or breastfeeding.

• You suffer from serious liver or kidney disease.

Safety Advice

Precautions

• Regular blood tests are needed to monitor bone marrow and organ function.

• Use reliable contraception during treatment.

• Avoid contact with people who have infections.

Concerns & Warnings

• May cause nausea, vomiting, liver or lung problems.

• Long-term use can increase the risk of secondary cancers.

• Can significantly reduce bone marrow activity, leading to infection or bleeding risk.

Lifestyle & Supportive Care

• Stay Active – Gentle exercise to boost energy.

• Get Enough Rest – Sleep and relaxation aid recovery.

• Manage Stress – Yoga, meditation, or breathing exercises.

• Eat Healthy – Balanced diet rich in protein, fruits, and vegetables.

• Avoid Alcohol & Smoking – These can weaken immunity and slow recovery.

• Stay Hydrated – Drink plenty of water and herbal teas.

Drug Interactions

• Avoid combining Lomustine with other chemotherapy drugs unless prescribed.

• Be cautious with blood thinners (higher bleeding risk).

• Do not take live vaccines while on treatment.

• Inform your doctor about all medications, supplements, and herbal remedies before starting therapy.

Buy Lomustine Capsules

Onco India International is a trusted supplier, wholesaler, manufacturer, and exporter of Lomustine Capsules. If you are looking for high-quality Lomustine, including Lomustine 40 mg, 100 mg, and 130 mg capsules, feel free to contact Onco India International for genuine products and reliable service.