Mefloquine and Artesunate Tablets are a combination medicine used for the treatment of malaria, a disease caused by Plasmodium parasites transmitted through mosquito bites.

Here are the key details:

• Composition:

  • Mefloquine – an antimalarial that kills malaria parasites by interfering with their growth and reproduction in red blood cells.

  • Artesunate – an antimalarial derived from artemisinin that rapidly kills malaria parasites in the bloodstream.

• Main Use:

  • Treatment of acute malaria infections, including strains resistant to other antimalarial drugs.

  • Sometimes used when a rapid reduction of parasite load is needed.

• How It Works:

  • Artesunate quickly reduces the number of malaria parasites in the blood.

  • Mefloquine works more slowly to eliminate remaining parasites and prevent recurrence. Together, they provide effective combination therapy.

• Administration: Taken orally, usually once daily for a few days, as prescribed by the doctor. It is important to complete the full course even if symptoms improve.

• Common Side Effects: Nausea, vomiting, dizziness, headache, mild diarrhea, or sleep disturbances.

• Serious Concerns: Rarely, it may cause heart rhythm changes, severe allergic reactions, psychiatric effects (anxiety, vivid dreams, or hallucinations), or liver problems.

• Precautions:

  • Not recommended in patients with a history of heart rhythm problems, psychiatric disorders, or severe liver disease.

  • Inform the doctor about all other medications to avoid interactions.

  • Avoid driving or operating machinery if dizziness or sleep disturbances occur.

• Storage: Store at room temperature, away from moisture, heat, and direct sunlight.