Nefopam Tablets are a non-opioid pain-relieving medicine used for the treatment of moderate to moderately severe pain. They are different from NSAIDs and opioids, as they work through a unique mechanism.

Here are the key details:

• Main Use:

  • Relief of acute and chronic pain conditions, including postoperative pain, musculoskeletal pain, or pain not well controlled by common analgesics.

  • Sometimes used as an alternative when NSAIDs or opioids are not suitable.

• How It Works:

  • Nefopam acts on the central nervous system by inhibiting the reuptake of certain neurotransmitters (serotonin, norepinephrine, and dopamine).

  • This reduces pain signaling in the brain and spinal cord.

• Administration:

  • Taken orally, usually 3 times a day (depending on severity of pain and doctor’s instructions).

  • Best taken with water, with or without food.

• Common Side Effects:

  • Nausea, dry mouth, sweating, dizziness, nervousness, or insomnia.

  • May cause blurred vision or drowsiness in some people.

• Serious Concerns:

  • Can increase the risk of seizures, especially in those with seizure disorders.

  • Should be avoided in patients with a history of heart disease (may cause palpitations or rapid heartbeat).

  • Rarely may cause confusion, hallucinations, or urinary retention.

• Precautions:

  • Not recommended for people with a history of epilepsy or uncontrolled convulsions.

  • Caution in patients with glaucoma or urinary retention.

  • Avoid alcohol, as it can worsen side effects like dizziness or drowsiness.

  • Should not be combined with other medicines that act on the brain without medical advice.

• Storage: Store at room temperature, away from heat, moisture, and sunlight.