Oflaxacillin and Ornidazole Tablets are a combination antibacterial and antiprotozoal medicine used to treat mixed bacterial and protozoal infections.

Here are the key details:

• Main Uses:

  • Treatment of gastrointestinal infections caused by bacteria and protozoa (such as diarrhea or dysentery).

  • Management of respiratory tract infections with bacterial and anaerobic components.

  • Sometimes prescribed for gynecological or dental infections where mixed infections are suspected.

• How It Works:

  • Oflaxacillin: A type of fluoroquinolone antibiotic that kills or stops the growth of bacteria by interfering with their DNA replication.

  • Ornidazole: Works against anaerobic bacteria and protozoa by damaging their DNA and preventing replication.

  • Together, they cover a broad range of bacterial and protozoal infections.

• Administration:

  • Taken orally, usually 1–2 times daily as prescribed by the doctor.

  • Should be taken with food to reduce stomach irritation.

  • Complete the full course even if symptoms improve to prevent resistance.

• Common Side Effects:

  • Nausea, vomiting, mild stomach upset, diarrhea.

  • Headache, dizziness, or metallic taste in the mouth (from ornidazole).

• Serious Concerns:

  • Rare allergic reactions (rash, swelling, difficulty breathing).

  • May rarely affect liver function or blood counts.

  • Excessive or prolonged use may lead to antibiotic resistance or imbalance in gut flora.

• Precautions:

  • Not recommended in patients with severe liver or kidney disease without medical supervision.

  • Avoid alcohol while taking ornidazole, as it may cause nausea, flushing, or headache.

  • Inform the doctor of other medications to prevent drug interactions.

• Storage: Store at room temperature, away from moisture, heat, and direct sunlight.

👉 This combination is often used for mixed infections where both aerobic bacteria and anaerobic bacteria/protozoa may be present, offering broader coverage than a single drug.