Ofloxacin 400 mg Tablets are a fluoroquinolone antibiotic used to treat moderate to severe bacterial infections.

Here are the key details:

• Main Uses:

  • Treatment of respiratory tract infections such as pneumonia, bronchitis, or sinus infections.

  • Management of urinary tract infections (UTIs), including complicated infections.

  • Treatment of skin and soft tissue infections caused by susceptible bacteria.

  • Sometimes used for gastrointestinal infections caused by bacteria, or certain sexually transmitted infections like gonorrhea.

• How It Works:

  • Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication.

  • This prevents bacterial growth and kills bacteria, allowing the body to clear the infection.

• Administration:

  • Taken orally, usually once or twice daily depending on the type and severity of infection.

  • Can be taken with or without food.

  • The full course must be completed, even if symptoms improve, to prevent antibiotic resistance.

• Common Side Effects:

  • Nausea, vomiting, stomach upset, diarrhea.

  • Dizziness, headache, or mild skin rash.

  • Rarely, temporary changes in taste or metallic taste.

• Serious Concerns:

  • Risk of tendon inflammation or rupture, particularly in older adults or those taking corticosteroids.

  • Rare allergic reactions or severe skin reactions.

  • May affect liver or kidney function in susceptible individuals.

  • Can increase sensitivity to sunlight, leading to sunburn.

  • Rare neurological effects like confusion, tremors, or seizures.

• Precautions:

  • Avoid excessive sun exposure; use sunscreen or protective clothing.

  • Inform the doctor of all other medications to avoid interactions, especially blood thinners, antiarrhythmics, or corticosteroids.

  • Use with caution in patients with kidney problems, tendon disorders, or neurological conditions.

  • Not usually recommended for children or pregnant women unless specifically prescribed.

• Storage: Store at room temperature, away from moisture, heat, and direct sunlight.

👉 Ofloxacin 400 mg is used for more serious or complicated infections compared to lower doses, and careful adherence to the prescribed course is important due to tendon, liver, and kidney risks.