Ofloxacin + Ketorolac Combination

This is a combination eye drop that contains:

• Ofloxacin – a fluoroquinolone antibiotic

• Ketorolac – a non-steroidal anti-inflammatory drug (NSAID)

It is used when an eye infection needs antibacterial treatment along with pain and inflammation control — especially after surgery or in painful bacterial conjunctivitis.

Components and Their Roles

1. Ofloxacin

   • Type: Fluoroquinolone antibiotic

   • Action: Blocks bacterial DNA enzymes (DNA gyrase, topoisomerase IV), stopping growth and killing bacteria.

   • Purpose: Treats bacterial infections such as conjunctivitis, keratitis, or post-surgical infection risk.

2. Ketorolac

   • Type: NSAID (anti-inflammatory)

   • Action: Reduces prostaglandin production, which decreases inflammation, redness, and pain.

   • Purpose: Relieves eye discomfort without using steroids, avoiding steroid-related side effects.

Common Uses

• Bacterial conjunctivitis with pain and swelling

• Post-cataract or other eye surgery to prevent infection and reduce inflammation

• Keratitis or corneal ulcers with discomfort

• Situations where steroids should be avoided (glaucoma risk, delayed wound healing)

Advantages

• Combines infection control and pain relief in one medication

• Avoids steroid-related risks like increased eye pressure or delayed healing

• Convenient single treatment for patients needing both actions

Possible Side Effects

From Ofloxacin:

• Temporary stinging or irritation

• Mild eye redness

• Rare allergic reaction

From Ketorolac:

• Mild burning or stinging after application

• Rarely, delayed corneal healing with prolonged use

• Increased sensitivity in patients allergic to aspirin or other NSAIDs

Precautions

• Should be used as prescribed — avoid long-term use without medical supervision.

• Not suitable for viral or fungal eye infections.

• Wash hands before use and avoid contaminating the dropper tip.

• Inform the doctor if you have a history of NSAID allergy, bleeding disorders, or corneal problems.