Ramipril and Hydrochlorothiazide Tablets are a combination medication used to manage high blood pressure (hypertension).

Here are the key details:

• Main Uses:

  • Treatment of high blood pressure when a single medication is not sufficient.

  • Reduces the risk of heart attack, stroke, and heart failure in patients with hypertension.

  • Helps protect the kidneys in certain patients, particularly those with diabetes or proteinuria.

• How It Works:

  • Ramipril: An ACE inhibitor that relaxes blood vessels by blocking angiotensin-converting enzyme, reducing blood pressure and easing the heart’s workload.

  • Hydrochlorothiazide: A thiazide diuretic that removes excess salt and water from the body through urine, helping to lower blood pressure.

  • The combination provides a synergistic effect, controlling blood pressure more effectively than either drug alone.

• Administration:

  • Taken orally, usually once daily, with or without food.

  • Dosage is determined by the doctor based on blood pressure, kidney function, and overall health.

  • Regular monitoring of blood pressure and electrolytes is recommended.

• Common Side Effects:

  • Dizziness or lightheadedness, especially when standing up.

  • Mild cough (from ramipril).

  • Increased urination (from hydrochlorothiazide).

  • Fatigue, headache, or mild stomach upset.

• Serious Concerns:

  • Can cause high potassium (from ramipril) or low sodium/potassium (from hydrochlorothiazide).

  • Rare allergic reactions or swelling of face, lips, or throat (angioedema).

  • May worsen kidney function in susceptible individuals.

  • Low blood pressure (hypotension) in some patients.

• Precautions:

  • Inform your doctor if you have kidney disease, heart problems, or electrolyte imbalances.

  • Avoid potassium supplements or salt substitutes unless prescribed.

  • Do not use during pregnancy, especially in the second or third trimester.

  • Drink plenty of water to prevent dehydration.

  • Regular blood tests may be required to monitor kidney function and electrolytes.

• Storage: Store at room temperature, away from moisture, heat, and direct sunlight.

👉 Ramipril and Hydrochlorothiazide Tablets are effective for controlling blood pressure and reducing cardiovascular risk, but require monitoring of blood pressure, kidney function, and electrolyte levels for safe use.