Rotavirus Vaccine Injection

Category: Vaccine / Live attenuated or inactivated virus
Form: Injectable solution

Uses:

• Prevents rotavirus infection, which is a common cause of severe diarrhea and vomiting in infants and young children.

• Protects against rotavirus gastroenteritis, reducing hospitalizations and complications from dehydration.

Mechanism of Action:

• The vaccine contains live attenuated or inactivated rotavirus strains.

• Stimulates the immune system to produce antibodies against rotavirus.

• Provides active immunity, so the body can respond quickly if exposed to the virus in the future.

• Helps reduce viral replication in the gut, preventing severe gastrointestinal illness.

Administration:

• Given intramuscularly or subcutaneously, depending on the formulation.

• Usually administered in a series of doses according to the immunization schedule:

  • Typically starts at 6–8 weeks of age.

  • Subsequent doses given 4–8 weeks apart.

• Full protection is achieved after completing the recommended dose series.

Side Effects:

• Common: mild fever, irritability, redness, or swelling at the injection site.

• Less common: mild diarrhea or vomiting.

• Rare: allergic reactions or severe hypersensitivity.

Precautions:

• Avoid vaccination in infants with severe immunodeficiency or a history of severe allergic reaction to a previous dose.

• Monitor for adverse reactions following injection.

• Can be administered along with other routine childhood vaccines.

Summary:
The Rotavirus Vaccine Injection is used to prevent severe rotavirus infections in infants and young children. It works by stimulating the immune system to produce protective antibodies against rotavirus, reducing the risk of diarrhea, vomiting, and dehydration. Administered intramuscularly or subcutaneously in multiple doses, it is generally safe, with mild side effects such as fever or injection site reactions.