Sevelamer Hydrochloride Tablets

Product/Composition Sevelamer Hydrochloride Tablets
Strength 400mg, 800mg
Form Tablets
Production Capacity 10 Million Tablet/Month
Packaging 10 X 10 Tablets / Box
Package Insert/Leaflet Available upon request

Sevelamer Hydrochloride Tablets are a medication used to manage high phosphate levels in patients with chronic kidney disease (CKD) on dialysis.

Here are the key details:

  • Main Uses:

    • Treatment of hyperphosphatemia (high phosphate in the blood) in adults and children with CKD undergoing dialysis.

    • Helps prevent bone and cardiovascular complications associated with elevated phosphate levels.

  • How It Works:

    • Sevelamer hydrochloride is a non-absorbed phosphate binder.

    • It binds dietary phosphate in the intestines, preventing its absorption into the bloodstream.

    • Bound phosphate is then excreted through the stool, lowering blood phosphate levels.

  • Administration:

    • Taken orally, usually with meals, as prescribed by the doctor.

    • Tablets should be swallowed whole or crushed and mixed with water or soft food if needed.

    • Dosage is individualized based on blood phosphate levels and patient response.

  • Common Side Effects:

    • Nausea, stomach discomfort, or bloating.

    • Constipation or diarrhea.

    • Mild skin rash in some patients.

  • Serious Concerns:

    • Rare cases of intestinal obstruction or severe constipation.

    • Electrolyte imbalances, including changes in bicarbonate, calcium, or other minerals.

    • Allergic reactions are uncommon but possible.

  • Precautions:

    • Inform your doctor about other medications, as Sevelamer can reduce the absorption of certain drugs, including some antibiotics and vitamins.

    • Regular blood tests are required to monitor phosphate, calcium, and bicarbonate levels.

    • Use with caution in patients with a history of bowel obstruction or severe gastrointestinal disease.

    • Maintain proper hydration and follow dietary guidance for phosphate intake.

  • Storage: Store at room temperature, away from moisture, heat, and direct sunlight.

👉 Sevelamer Hydrochloride Tablets are effective for lowering phosphate levels in kidney disease patients, helping prevent complications, but require monitoring of electrolytes and bowel health.