Temozolomide Capsules Information

Highlights for Temozolomide

Temozolomide is an oral chemotherapy medicine widely used in the treatment of brain tumours, including glioblastoma multiforme (GBM) and anaplastic astrocytoma. It belongs to a class of alkylating agents that interfere with the DNA of cancer cells, preventing their growth and survival.

It is usually prescribed in capsule form, with dosage tailored to the patient’s medical condition, body weight, and stage of treatment.

Temozolomide was first introduced in 1990, and in 2005, the FDA approved it for the treatment of glioblastoma, marking a significant advancement in brain cancer therapy. It is often combined with surgery and radiotherapy, improving both survival rates and quality of life for patients.

What are Temozolomide Capsules?

Temozolomide Capsules are an effective option for controlling brain tumours such as glioblastoma multiforme (GBM) and anaplastic astrocytoma. Unlike intravenous chemotherapy, Temozolomide is usually taken on an outpatient basis, offering patients more convenience.

The medicine is generally given in cycles—commonly five consecutive days of treatment followed by a 23-day break. This cyclic therapy has become a standard regimen for patients with GBM and other brain cancers.

Uses of Temozolomide Capsules

• Treatment of Glioblastoma Multiforme (GBM): First-line treatment for aggressive brain cancer.

• Treatment of Anaplastic Astrocytoma: Used in rare malignant tumours where other treatments may not be effective.

• Off-label Use: Sometimes prescribed for other cancers, depending on oncologist’s evaluation.

How to Take Temozolomide Capsules

• Always follow your doctor’s prescription carefully.

• Dosage depends on weight, cancer type, and treatment cycle.

• Take at the same time every day, preferably 1 hour before or 2 hours after meals.

• Swallow whole with a glass of water—do not crush or chew.

• Wash hands thoroughly after handling capsules. Avoid touching broken or damaged capsules.

How Temozolomide Works

Temozolomide is a pro-drug, which converts into MTIC in the body. MTIC adds methyl groups to DNA (especially guanine bases), disrupting the DNA structure and triggering apoptosis (programmed cell death) in cancer cells.

Because it can cross the blood–brain barrier, it is especially effective against brain tumours.

Benefits of Temozolomide Capsules

• Effective against brain tumours (GBM and anaplastic astrocytoma).

• Convenient oral dosage compared to IV chemotherapy.

• Crosses the blood–brain barrier, making it suitable for brain cancer treatment.

• Works on both new and recurrent tumours.

• Explored for off-label uses in other cancers.

Possible Side Effects

• Nausea & vomiting

• Loss of appetite

• Constipation

• Fatigue

• Flushing

• Anemia

• Neutropenia (low white blood cell count)

Precautions & Safety Advice

• Inform your doctor about any pre-existing conditions (liver, kidney, infections, allergies).

• Avoid during pregnancy or breastfeeding; may affect fertility in both men and women.

• Suppresses immunity—avoid contact with sick individuals.

• Regular blood monitoring is necessary to track blood counts.

• Avoid alcohol and unhealthy habits to reduce risks.

Overdose & Missed Dose

• Overdose: May cause bone marrow suppression and dangerously low blood counts. Seek immediate medical help.

• Missed Dose: Take as soon as you remember, but do not double the next dose.

Storage

Store Temozolomide Capsules at room temperature, away from moisture and heat.

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Is Temozolomide a Painkiller or Narcotic?

No. Temozolomide is not a painkiller and should not be considered a narcotic. It is a chemotherapy drug specifically for cancer treatment.

Where to Buy Temozolomide Capsules?

Onco India International is a trusted manufacturer, supplier, and exporter of Temozolomide Capsules. We provide high-quality formulations such as Temozolomide 20 mg, 100 mg, 250 mg capsules for cancer care.

If you are looking for genuine Temozolomide Capsules, feel free to contact Onco India International for reliable supply and export services.