Testosterone Propionate Injection

Category: Androgen / Anabolic-androgenic steroid
Form: Injectable solution (intramuscular)

Uses:

• Hormone replacement therapy in males with primary or secondary hypogonadism (low testosterone levels).

• Delayed puberty in adolescent boys due to testosterone deficiency.

• Certain breast cancers in women (rare cases).

• Occasionally used in performance enhancement or bodybuilding, though non-medical use is not recommended.

Mechanism of Action:

• Testosterone propionate is a short-acting ester of testosterone.

• Binds to androgen receptors, promoting protein synthesis, muscle growth, and development of male secondary sexual characteristics.

• Supports spermatogenesis, libido, bone density, and overall male reproductive function.

• Rapidly absorbed from the injection site, leading to shorter duration of action, requiring more frequent administration than longer esters like enanthate or cypionate.

Administration:

• Administered intramuscularly, commonly in the gluteal or thigh muscle.

• Dosage and frequency depend on patient age, testosterone levels, and clinical condition.

• Typically injected every 2–3 days due to its short half-life.

Side Effects:

• Androgenic effects: acne, oily skin, increased body hair, hair loss.

• Cardiovascular: elevated blood pressure, changes in cholesterol, increased heart disease risk.

• Hormonal disturbances: suppression of natural testosterone production, testicular atrophy, infertility.

• Other: mood changes, aggression, fluid retention, rare liver issues.

Precautions:

• Avoid in patients with prostate or breast cancer in men, or severe heart, liver, or kidney disease.

• Regular monitoring of testosterone levels, hematocrit, liver function, and prostate health is recommended.

• Women and children should avoid exposure due to risk of virilization.

• Use caution in patients with cardiovascular risk factors.

Summary:
Testosterone Propionate Injection is a short-acting testosterone ester used for hormone replacement in men with low testosterone or delayed puberty. It promotes male sexual characteristics, muscle growth, and reproductive function by binding to androgen receptors. Administered intramuscularly every few days, it requires careful monitoring due to potential androgenic, cardiovascular, and hormonal side effects.