Doxorubicin hydrochloride Doxoruba
| Product/Composition | Doxorubicin Hydrochloride |
|---|---|
| Strength | 10mg |
| Form | Injection |
| Production Capacity | 10 Million Vials/Month |
| Packaging | 1 Vial / Box |
| Therapeutic use | Cancer Treatment / Chemotherapy |
| Package Insert/Leaflet | Available upon request |
| Brand Name | Doxoruba |
Doxoruba contains Doxorubicin Hydrochloride, an anthracycline antineoplastic medicine used as part of chemotherapy regimens for the treatment of various types of cancer. Doxorubicin works through multiple mechanisms, including DNA intercalation and inhibition of topoisomerase II, which interfere with cancer-cell replication and survival.
Doxorubicin Hydrochloride is administered intravenously by qualified healthcare professionals. The dose and treatment schedule depend on the cancer type, chemotherapy regimen, body-surface area, previous treatments, organ function, and overall patient condition.
What is Doxorubicin Hydrochloride?
Doxorubicin Hydrochloride is an anthracycline antibiotic and cytotoxic chemotherapy agent. It interferes with DNA replication and repair by intercalating into DNA and inhibiting topoisomerase II. It can also generate free radicals that contribute to cellular damage.
Doxorubicin may be used alone or in combination with other anticancer medicines according to established treatment protocols.
Benefits / Uses
Doxoruba (Doxorubicin Hydrochloride) may be used as part of chemotherapy regimens for:
- Breast cancer
- Hodgkin lymphoma
- Non-Hodgkin lymphoma
- Leukemias
- Sarcomas
- Multiple myeloma
- Ovarian cancer
- Bladder cancer
- Gastric cancer
- Other malignancies according to specific treatment protocols
The exact indication and chemotherapy combination should be determined by the treating oncologist.
Dosage Guidelines
Doxorubicin Hydrochloride is administered intravenously, with the dose individualized according to the prescribed chemotherapy protocol.
Important considerations include:
- Dosage is commonly calculated according to body-surface area and the specific treatment regimen.
- Complete blood counts should be monitored during treatment.
- Liver function may need to be assessed because hepatic impairment can affect dosing.
- Cardiac function may be evaluated before and during treatment.
- The cumulative lifetime dose is an important consideration because the risk of cardiotoxicity increases with cumulative exposure.
- Antiemetic medicines may be prescribed to help manage chemotherapy-related nausea and vomiting.
Doxorubicin should only be administered under specialist medical supervision.
Wholesale & Supply
Doxoruba (Doxorubicin Hydrochloride) can be considered for pharmaceutical wholesale and institutional supply, subject to applicable regulatory requirements, market authorization, and destination-country regulations.
For bulk procurement, buyers can request information regarding:
- Available strengths and presentations
- Packaging configuration
- Batch details
- Certificate of Analysis (CoA)
- Manufacturing documentation
- Export and shipping documentation
Buying Online
Doxorubicin Hydrochloride is a prescription chemotherapy medicine and should be sourced only through authorized pharmaceutical distributors, hospitals, pharmacies, or other licensed healthcare channels.
Reviews
Individual responses to Doxorubicin can vary according to cancer type, treatment regimen, dosage, and patient-specific factors. Treatment outcomes and tolerability should be evaluated by the treating oncology team.
Quality Assurance
Doxorubicin Hydrochloride injectable products should undergo appropriate pharmaceutical quality-control testing for parameters such as identity, strength, purity, sterility, and other applicable specifications for injectable medicines.
Frequently Asked Questions
What is Doxoruba used for?
Doxoruba contains Doxorubicin Hydrochloride and is used as part of chemotherapy regimens for various cancers, including breast cancer, lymphomas, leukemias, sarcomas, ovarian cancer, and bladder cancer.
What type of medicine is Doxorubicin Hydrochloride?
Doxorubicin Hydrochloride is an anthracycline antibiotic and cytotoxic chemotherapy medicine.
How is Doxoruba administered?
Doxoruba is administered intravenously by qualified healthcare professionals according to the prescribed chemotherapy protocol.
What are the important side effects of Doxorubicin?
Important adverse effects may include reduced blood-cell counts, nausea and vomiting, mouth sores, hair loss, and tissue injury if the medicine leaks outside the vein. Doxorubicin can also cause cardiac toxicity, particularly with increasing cumulative exposure.
Why is heart monitoring important with Doxorubicin?
Doxorubicin can cause damage to the heart muscle. Depending on the treatment plan and individual risk factors, cardiac function may therefore be assessed before and during therapy.
Can Doxorubicin be used with other chemotherapy medicines?
Yes. Doxorubicin is commonly incorporated into combination chemotherapy regimens depending on the cancer diagnosis and treatment protocol.
Who should administer Doxorubicin?
Doxorubicin should be administered by qualified healthcare professionals experienced in cytotoxic chemotherapy, with appropriate monitoring facilities available.
Conclusion
Doxoruba (Doxorubicin Hydrochloride) is an established anthracycline chemotherapy medicine used in numerous oncology treatment protocols. Its multiple mechanisms of action against cancer-cell DNA make it an important component of chemotherapy for a broad range of malignancies. Because Doxorubicin can cause significant hematological and cardiac toxicities, treatment requires specialist supervision, appropriate laboratory monitoring, and careful consideration of cumulative exposure.



