Oxaliplatin Oxa
| Product/Composition | Oxaliplatin |
|---|---|
| Strength | 50mg, 100mg |
| Form | Injection |
| Production Capacity | 10 Million Vials/Month |
| Packaging | 1 Vial / Box |
| Therapeutic use | Colorectal Cancer / Gastrointestinal Cancer |
| Package Insert/Leaflet | Available upon request |
| Brand Name | Oxa |
Oxa contains Oxaliplatin, a platinum-based antineoplastic medicine used as part of combination chemotherapy, particularly in the treatment of colorectal cancer and selected gastrointestinal malignancies.
Oxaliplatin works by forming platinum-DNA complexes that cause DNA cross-linking. This interferes with DNA replication and transcription, helping inhibit the growth and survival of susceptible cancer cells.
Oxaliplatin is administered by intravenous infusion and is commonly used in combination chemotherapy regimens such as FOLFOX.
What is Oxaliplatin?
Oxaliplatin is a platinum-based cytotoxic chemotherapy agent. It damages cancer-cell DNA through platinum-mediated cross-linking, preventing malignant cells from properly replicating and dividing.
Benefits / Uses
Oxa (Oxaliplatin) may be used as part of treatment protocols for:
- Colorectal cancer
- Colon cancer
- Rectal cancer
- Advanced or metastatic colorectal cancer
- Selected gastrointestinal malignancies according to specialist oncology protocols
It is commonly used in combination with 5-fluorouracil and leucovorin.
Dosage Guidelines
Oxaliplatin dosage depends on the specific cancer, chemotherapy regimen, body surface area, organ function, previous treatment, and clinical response.
- Administer only under specialist oncology supervision.
- Given by intravenous infusion.
- Complete blood counts should be monitored during treatment.
- Renal and hepatic function may be assessed as appropriate.
- Neurological symptoms should be monitored, particularly peripheral sensory neuropathy.
- Dose modification or treatment interruption may be necessary for significant toxicity.
- Administration should follow the approved product information and chemotherapy protocol.
Wholesale & Supply
Oxa (Oxaliplatin) may be supplied for pharmaceutical wholesale and institutional procurement, subject to applicable regulatory requirements.
Bulk procurement enquiries may include:
- Available strengths and presentations
- Packaging configuration
- Certificate of Analysis (CoA)
- Batch information
- Manufacturing documentation
- Export and shipping documentation
Buying Online
Oxaliplatin is a prescription injectable chemotherapy medicine and should be sourced through authorized pharmaceutical distributors, hospitals, or licensed healthcare channels.
Reviews
Individual responses to Oxaliplatin vary according to cancer type, disease stage, chemotherapy combination, dosage, and patient-specific factors. Treatment response and tolerability should be evaluated by the treating oncology team.
Quality Assurance
Oxaliplatin products should undergo appropriate pharmaceutical quality-control testing according to applicable standards, including relevant testing for identity, potency, purity, sterility, and other formulation-specific requirements.
Frequently Asked Questions
What is Oxa used for?
Oxa contains Oxaliplatin and is primarily used as part of combination chemotherapy for colorectal cancer and selected gastrointestinal malignancies.
What type of medicine is Oxaliplatin?
Oxaliplatin is a platinum-based cytotoxic chemotherapy medicine.
How does Oxaliplatin work?
Oxaliplatin forms platinum-DNA complexes and cross-links DNA, interfering with DNA replication and transcription in susceptible cancer cells.
How is Oxa administered?
Oxa is administered by intravenous infusion under the supervision of qualified healthcare professionals.
Is Oxaliplatin used with other chemotherapy medicines?
Yes. Oxaliplatin is commonly combined with 5-fluorouracil and leucovorin in regimens such as FOLFOX.
What are the important side effects of Oxaliplatin?
Potential adverse effects include peripheral sensory neuropathy, nausea, vomiting, diarrhea, fatigue, reduced blood-cell counts, and hypersensitivity reactions.
Can Oxaliplatin cause nerve-related side effects?
Yes. Peripheral sensory neuropathy is a characteristic toxicity of Oxaliplatin. Acute sensory symptoms may be triggered or worsened by exposure to cold.
Does Oxaliplatin require laboratory monitoring?
Yes. Blood counts and relevant organ-function tests are generally monitored during treatment according to the prescribed chemotherapy protocol.
Who should administer Oxa?
Oxa should be prescribed and administered by qualified healthcare professionals experienced in cancer chemotherapy.
Conclusion
Oxa (Oxaliplatin) is a platinum-based cytotoxic chemotherapy medicine used principally in combination regimens for colorectal cancer and selected gastrointestinal malignancies. By damaging cancer-cell DNA, it interferes with malignant-cell replication and growth. Because treatment can cause hematological, gastrointestinal, neurological, and hypersensitivity-related toxicities, specialist supervision and appropriate monitoring are essential.

